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Hydrocodone vs. Tramadol
What are Hydrocodone and Tramadol?
Hydrocodone and tramadol
are two extremely effective pain-reducing opioid medications available
globally. They both are opioid analgesics and treat moderate to severe pain
from cancer and other chronic conditions. Both of these drugs work by altering
the way our brain responds to pain signals. As both of them are potent and
exceptionally effective, they come along with some side effects.
Hydrocodone
Hydrocodone, sold
under the brand name of Zohydro ER, among others, is generally used when other
medications do not show many positive effects in reducing pain and providing
the patient with relief. This opioid pain reliever also works as a cough
suppressant in adults. This medicine, combined with acetaminophen and ibuprofen,
is typically available in the market for pain reduction.
People in the United
States are the biggest consumers of this opioid drug, as about 99% of the
supply gets consumed here. It comes from opium poppy after converting it into codeine.
It works by interfering with the pain signals headed towards the brain and
changes how the brain perceives and reacts to it. Hydrocodone is a
habit-forming drug, which essentially means that you need to have it in
moderation and not overuse it.
Tramadol
Tramadol, sold under
Ultram’s brand name, among others, is a narcotic-like pain reliever used to
treat moderate to moderately severe pain. Apart from its generic version, you
may find tramadol combined with acetaminophen in the global market for reducing
pain caused by illnesses like fibromyalgia and cancers. Tramadol is a
controlled substance, which means you cannot buy it without a doctor’s
prescription.
It is available as a
generic medicine here in the United States and is one of the most prescribed
prescription medications. Tramadol works by attaching to the brain’s receptors,
and after that, changing the way the brain reads pain signals. Tramadol also
allows the two chemical messengers, namely norepinephrine and serotonin, to
remain available for an extended period, blocking the pain signals from reaching
the brain.
Working of Hydrocodoneand Tramadol
As both hydrocodone
and tramadol come from the opioid analgesics family, they work similarly to
other family members. These work quite a lot like endorphins, a substance found
in the human brain. Endorphins bind themselves with the brain’s receptors,
resulting in the receptors decreasing the pain signals’ intensity reaching the
brain via nerves. These prescription drugs do their job in the same way by
lowering the pain signals and limiting the mind to become fully aware of the
body’s pain.
As hydrocodone and
tramadol interact with the central nervous system directly, one should not take
them without prescription and extreme supervision. Buying these medications
without consulting a doctor is certainly not the safest route as some side
effects are too associated with the drug. One should not take lightly at any
point in time, especially when the patient is already dealing with other illnesses.
Side Effects Of Hydrocodone and Tramadol
Both hydrocodone and tramadol
are opioids that are credible and trustworthy when talking about pain
reduction. The working of both of these drugs occurs in the brain and central
nervous system, making their usage critical. They have some side effects too
associated with them, which you must consider before purchasing these
prescription drugs. You need to get in touch with your doctor if you develop
severe hydrocodone or tramadol side effects. Although most people encounter
mild side effects, we can still not ignore the fact that both are potent
medicines.
Hydrocodone
The side effects of
hydrocodone are:
·
Dizziness
·
Drowsiness
·
Loss of
Appetite
·
Constipation
·
Nausea
·
Vomiting
·
Low blood
pressure
·
Confusion
·
Respiratory
Depression
·
Gastric
Obstruction
·
Mood
Swings
·
Hypersensitivity
Reactions
·
Skin Rash
·
Trouble
Breathing
Tramadol
Some tramadol side
effects are:
·
Flushing
·
Congestion
·
Headache
·
Itching
·
Weakness
·
Sore
throat
·
Seizures
·
Drowsiness
·
Dizziness
·
Vomiting
·
Nausea
·
Constipation
·
Lack of
appetite
·
Hypersensitivity
·
Mood
Swings
Risk factors
Some people might be
at a higher risk of side effects from hydrocodone and tramadol due to their age
or a medical condition. People with the following medical problems can
experience increased side effects of these drugs:
·
Kidney
disease
·
Live
disease
·
Chronic
obstructive pulmonary disease
·
Mental
health problems
Also, people with
depression who consume tramadol are at a higher risk of suicide.
Interactions
Inform your doctor
about all the prescription, over-the-counter, non-prescription drugs, herbal
supplements, or vitamins you are using before starting the treatment with
either hydrocodone or tramadol. In addition to the medications, substances like
alcohol and marijuana can also interact with these drugs and cause undesirable
effects.
Avoid using these
medicines with sleep-inducing medications, including cough and cold drugs, as
these increase the sedating effects of hydrocodone and tramadol.
If you are not sure
about any medicine’s effects, try consulting a doctor or pharmacist before
mixing it with either hydrocodone or tramadol.
Warnings
Hydrocodone contains a
black box warning for potential misuse. DEA states that hydrocodone is the most
abused drug among all the opioids.
While hydrocodone is
the more dangerous one of the two, you can quickly develop tolerance from
either of them if you use them for an extended time. When you build a medicinetolerance, you will need more of the drug to achieve the desired results. When
a person starts taking more and more of these medications, they can develop a
dependence on them.
Those with a history
of alcohol or substance abuse are more prone to become dependent on hydrocodone
and tramadol. Any unwanted effects occurring due to delay in taking medicine
can be a sign of dependence; make sure to let the doctor know right away if
something similar happens to you.
When you use these
medicines for a prolonged period, try not to stop consuming them abruptly.
Doing so will result in undesirable withdrawal symptoms. Tell your doctor when
you are ready to terminate the treatment. A
professional will lower your dosage gradually to prevent withdrawal symptoms.
Which one to take?
Before choosing either
hydrocodone or tramadol, try discussing all the underlying medical conditions
you have and the drug you are consuming with a doctor. Also, inform them if you
ever had an alcohol or substance abuse problem.
After considering all the factors related to your mental and physical health, a doctor can recommend the best medication among the hydrocodone and tramadol.
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